RAF Typhoon fighter aircraft have conducted a mission with France's air force in a coordinated attack on an subterranean weapons facility in Syria used by the IS group, according to the UK Ministry of Defence.
The location, located using reconnaissance, was assessed as containing munitions and bombs, the statement said, and was positioned in mountains just north of the ancient city of Palmyra in Syria's central region.
"The RAF jets used laser-guided Paveway IV weapons to hit a several entry passages providing entry to the facility... early reports suggest the strike was effective," officials stated.
There was no sign of any harm to civilians in the strike late on Saturday and each participating jet returned safely, the defence officials confirmed.
The British jets were assisted by a Voyager aerial refuelling aircraft.
The Islamic State group - referred to as Daesh - imposed militant control over parts of both Syria and Iraq prior to its 2019 collapse.
"This strike demonstrates British leadership, and commitment to work closely with our partners, to eradicate any resurgence of IS and their dangerous and violent ideologies in the Middle East," UK Defence Secretary the Defence Secretary stated.
UK warplanes have performed overwatch operations over Syria to "prevent any attempted resurgence" of the group subsequent to its defeat at the Baghuz confrontation in the year 2019, the MoD reported.
"I extend gratitude to all the members of our armed forces participating in this operation for their expertise and their courage," the Defence Secretary said. "Including them were numerous UK service members on duty over the festive period. This action, to take out dangerous terrorists who endanger our security, shows how UK forces are prepared to act, continuously, keeping Britain secure domestically and powerful internationally."
During December, the US military executed what it called a "major assault" against Islamic State objectives in the country, after an assault resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The UN reports Islamic State still has an estimated 5,000 to 7,000 militants in Syria and Iraq.